Article

Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T cell receptor signalling

2024-04-03

Abstract excerpt

<h4>Background</h4> Over the past decade, cancer immunotherapies have revolutionised the treatment of melanoma; however, responses vary across patient populations. Recently, baseline tumour size has been identified as an independent prognostic factor for overall survival in melanoma patients receiving immune checkpoint inhibitors (ICIs). MG1 is a novel oncolytic agent with broad tumour tropism that has recently e...

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Literature Corpus work: 599bc2f6-53ce-53b2-8dbf-80783b2bbe81
DOI: 10.1101/2024.04.02.587705

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