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Caerin 1.1 and 1.9 peptides halt B16 melanoma metastatic tumours via expanding cDC1 and reprogramming tumour macrophages

2024-08-10

Abstract excerpt

<title>Abstract</title> <p>Background Cancer immunotherapy, particularly immune checkpoint inhibitors (ICBs) such as anti-PD-1 antibodies, has revolutionized cancer treatment, although response rates vary among patients. Previous studies have demonstrated that caerin 1.1 and 1.9, host-defence peptides from the Australian tree frog, enhance the effectiveness of anti-PD-1 and therapeutic vaccines in a murine TC-1...

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Literature Corpus work
f73128e4-8403-5dff-9eac-7bc6aea00fc6
DOI
10.21203/rs.3.rs-4671312/v1
Open publication

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Caerin 1.1 and 1.9 peptides halt B16 melanoma metastatic tumours via expanding cDC1 and reprogramming tumour macrophagesDOI 10.21203/rs.3.rs-4671312/v1
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