Article

Systemic effects of melanoma-secreted MIDKINE in the inhibition of dendritic cell differentiation and function

2022-12-31

Abstract excerpt

<h4>ABSTRACT</h4> Cutaneous melanomas are a prime example of potentially immunogenic tumors, and as such, ideal targets for immune therapy. These lesions have the largest mutational burden described to date, and accumulate a broad spectrum of post-transcriptional and translational alterations that could conceptually result in a plethora of neoantigens for immune recognition. However, a significant fraction of met...

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Literature Corpus work: 201d6a16-088d-5764-b4f0-561261ce80c9
DOI: 10.1101/2022.12.28.521901

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