Article

A genome wide search for non-additive allele effects identifies <i>PSKH2</i> as involved in the variability of Factor V activity

2024-02-09

Abstract excerpt

<h4>Background</h4> Factor V (FV) is a key molecular player in the coagulation cascade. FV plasma levels have been associated with several human diseases, including thrombosis, bleeding and diabetic complications. So far, two genes have been robustly found through genome wide association analyses to contribute in the inter-individual variability of plasma FV levels: structural F5 gene and PLXDC2. <h4>Methods</h4>...

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Literature Corpus work: 598c69b9-8175-5014-81ad-38e0ae42fa24
DOI: 10.1101/2024.02.08.579474

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A genome wide search for non-additive allele effects identifies <i>PSKH2</i> as involved in the variability of Factor V activityDOI 10.1101/2024.02.08.579474Read

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