Article

Inflammatory Bowel Disease and Neurodegenerative Disorders: Integrated Evidence from Mendelian Randomization, Shared Genetic Architecture and Transcriptomics

2022-05-25

Abstract excerpt

<h4>Objective</h4> Published observational studies have revealed the connection between inflammatory bowel disease (IBD) and neurodegenerative disorders, whereas the causality remains largely unclear. Our study aims to assess the causality and identify the shared genetic architecture between IBD and neurodegenerative disorders. <h4>Design</h4> A series of two-sample Mendelian randomization analyses were performed...

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Literature Corpus work: 598491c1-c7aa-58b7-b5a3-1d37f4f55189
DOI: 10.1101/2022.05.23.22275264

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