Article
Are neurodegenerative diseases associated with an increased risk of inflammatory bowel disease? A two-sample Mendelian randomization study.
Frontiers in immunology - 1 Jan 2022
Cui Guanghui, Li Shaojie, Ye Hui, Yang Yao, Huang Qiuyue, Chu Yingming, Shi Zongming, Zhang Xuezhi
Abstract excerpt
Background: Several studies have shown that neurodegenerative diseases (e.g., Parkinson's disease [PD] and Alzheimer's disease [AD]) are associated with inflammatory bowel disease (IBD), but the causality and direction of their associations remain unclear. Mendelian randomization (MR) studies have explored the causal effects of IBD on PD and AD. However, only a few studies examined this reverse association. Thus,...
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