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Article

The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson's disease comorbidity.

Genome medicine - 14 May 2024

Kars Meltem Ece, Wu Yiming, Stenson Peter D, Cooper David N, Burisch Johan, Peter Inga, Itan Yuval

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) and Parkinson's disease (PD) are chronic disorders that have been suggested to share common pathophysiological processes. LRRK2 has been implicated as playing a role in both diseases. Exploring the genetic basis of the IBD-PD comorbidity through studying high-impact rare genetic variants can facilitate the identification of the novel shared genetic factors underlying...

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Source

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Identifiers

PMID: 38741190
DOI: 10.1186/s13073-024-01335-2
PMCID: PMC11092054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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