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Article

Association of Crohn's disease and ulcerative colitis with the risk of neurological diseases: a large-scale Mendelian randomization study.

Journal of human genetics - 1 Nov 2024

Wang Yinan, Jia Yiming, Xu Qingyun, Yang Pinni, Sun Lulu, Liu Yi, Chang Xinyue, He Yu, Shi Mengyao, Guo Daoxia, Zhang Yonghong, Zhu Zhengbao

Abstract excerpt

Observational studies suggested increased risks of Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) in patients with Crohn's disease (CD) and ulcerative colitis (UC). We aimed to assess the causality for the associations of CD and UC with the risks of AD, PD, and MS through a two-sample Mendelian randomization (MR) study. Independent single nucleotide polymorphisms associated with...

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Identifiers

PMID: 38951193
DOI: 10.1038/s10038-024-01271-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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