Article

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

2020-02-20

Abstract excerpt

Using incipient lines of the Collaborative Cross (CC), a murine genetic reference population, we previously identified a quantitative trait loci (QTL) associated with low SARS-CoV titer. In this study, we integrated sequence information and RNA expression of genes within the QTL to identify mucin 4 ( Muc4 ) as a high priority candidate for controlling SARS-CoV titer in the lung. To test this hypothesis, we infect...

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Literature Corpus work: 5964d0f7-061c-52ec-b990-d796189dcdd8
DOI: 10.1101/2020.02.19.957118

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