Article

Chemokine receptor 2-targeted molecular imaging in pulmonary fibrosis

2020-03-05

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a progressive, inflammatory lung disease that is monitored clinically by measures of lung function, without effective molecular markers of disease activity or therapeutic efficacy. Lung immune cells active in the pro-fibrotic process include inflammatory monocyte and interstitial macrophages that express the C-C motif chemokine receptor 2 (CCR2). CCR2 + monocyte lung influx...

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Literature Corpus work: 5912eaaa-5494-538a-801e-64c235673554
DOI: 10.1101/2020.03.04.960179

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