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Article

Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart

21 Jan 2019

Abstract excerpt

Rationale: Paradigm shifting studies have revealed that the heart contains functionally diverse populations of macrophages derived from distinct embryonic and adult hematopoietic progenitors. Under steady-state conditions, the heart is largely populated by CCR2− (C-C chemokine receptor type 2) macrophages of embryonic descent. After tissue injury, a dramatic shift in macrophage composition occurs whereby CCR2+...

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Share to Cardiac Fibrosis and Remodeling
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Identifiers

PMID: 30661445
DOI: 10.1161/circresaha.118.314030

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