Article

ACKR1-expressing venous endothelial cells establish a pro-fibrotic niche in pulmonary fibrosis

2026-08-03

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by excessive extracellular matrix deposition and irreversible architectural distortion of the lung. Fibrotic remodeling is driven by dynamic interactions among endothelial, fibroblast, epithelial and immune cells. Although pulmonary endothelial cells (ECs) are increasingly recognized as important contributors to IPF pathogenesis, the m...

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Literature Corpus work: 5e558de5-c83f-573a-afcb-eecfe5c4eda9
DOI: 10.64898/2026.07.31.742106

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