Article

Prevalent regulation of GATA2/3 and MSX2 on endogenous retrovirus-derived regulatory elements in human trophoblast stem cells

2022-08-03

Abstract excerpt

The placenta is an organ with extraordinary phenotypic diversity in eutherian mammals. Recent evidence suggests that numerous human placental enhancers are evolved from lineage-specific insertions of endogenous retroviruses (ERVs), yet the transcription factors (TFs) underlying their regulation remain largely elusive. Here, by first focusing on MER41, a primate-specific ERV family previously linked to placenta and...

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Identifiers and source

Literature Corpus work: 58df364b-60eb-57df-8109-f817f396ccc5
DOI: 10.1101/2022.08.02.502490

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