Back to search

Article

Deciphering the evolution of the transcriptional and regulatory landscape in human placenta

2020-09-12

Abstract excerpt

In mammals, the placenta mediates maternal-fetal nutrient and waste exchange and provides immunomodulatory actions that facilitate maternal-fetal tolerance. The placenta is highly diversified among mammalian species, yet the molecular mechanisms that distinguish the placenta of human from other mammals are not fully understood. Using an interspecies transcriptomic comparison of human, macaque, and mouse term place...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
183444c9-31a2-5565-865a-9355a676ed05
DOI
10.1101/2020.09.11.289686
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Deciphering the evolution of the transcriptional and regulatory landscape in human placentaDOI 10.1101/2020.09.11.289686
Endogenous Retroviruses Drive Lineage-Specific Regulatory Evolution across Primate and Rodent PlacentaeSemantic proximity
Regulation of human trophoblast gene expression by endogenous retrovirusesSemantic proximity
Endogenous Retroviruses and Placental Evolution, Development, and DiversitySemantic proximity
Retroviruses facilitate the rapid evolution of the mammalian placenta.Semantic proximity
The placenta goes viral: Retroviruses control gene expression in pregnancySemantic proximity
Regulation of human trophoblast gene expression by endogenous retrovirusesSemantic proximity
Regulation of human trophoblast gene expression by endogenous retrovirusesSemantic proximity
Transcriptome landscape of the human placentaSemantic proximity
Prevalent regulation of GATA2/3 and MSX2 on endogenous retrovirus-derived regulatory elements in human trophoblast stem cellsSemantic proximity
Cross-species insights into placental evolution and diseases at the single-cell resolutionSemantic proximity
Spatial multiomic landscape of the human placenta at molecular resolutionSemantic proximity
Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia riskSemantic proximity
Select a neighboring publication to make it the new centre.