Article

Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk

2026-01-23

Abstract excerpt

<h4>Background: </h4> Understanding the causes of the exceptional rate of evolution of the mammalian placenta is likely to aid the understanding of placental development and the aetiology of the human-specific pregnancy disorder pre-eclampsia (PE). As retroelements (REs) are often lineage-specific and known to be co-opted for placental functioning, here we consider the RE binding of GATA3 and DLX5, these transcrip...

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Literature Corpus work: 3f1e631c-ef07-5daa-9853-23e16b18b172
DOI: 10.64898/2026.01.20.700661

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