Article

MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge: implications for Rett Syndrome

2020-08-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Rett syndrome is a severe and progressive neurological disorder linked to mutations in the MeCP2 gene located on the X chromosome. So far it has not been established how the presence of a mutant form of MeCP2 can maintain essential regulation of immune responses to support the normal homeostasis of individuals. Since MeCP2 is mostly expressed as a “partially functional” prot...

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Literature Corpus work: 58cb502a-8a32-5dd3-b988-dccec1a2ec3b
DOI: 10.1101/2020.08.05.238683

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