Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Compromised immune/inflammatory responses in Rett syndrome.

Free radical biology & medicine - 20 May 2020

Pecorelli Alessandra, Cervellati Carlo, Cordone Valeria, Hayek Joussef, Valacchi Giuseppe

Abstract excerpt

Mutations in X-linked gene methyl-CpG-binding protein 2 (MECP2), a key transcriptional regulator, account for most cases of Rett syndrome (RTT), a devastating neurodevelopmental disorder with no known cure. Despite extensive research to elucidate MeCP2 functions, the mechanisms underlying RTT pathophysiology are still unclear. In addition to a variety of neurological symptoms, RTT also includes a plethora of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunity
Share to Lipid Metabolism
Share to Methyl-CpG-Binding Protein 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Rett Syndrome

Source

Identifiers

PMID: 32119978
DOI: 10.1016/j.freeradbiomed.2020.02.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Compromised immune/inflammatory responses in Rett syndrome.PMID 32119978Read ↗

Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome: Relationships with Aberrant Redox Homeostasis, Inflammation, and ω-3 PUFAs.Semantic proximity Read ↗

Exploring the possible link between MeCP2 and oxidative stress in Rett syndrome.Semantic proximity Read ↗

Subclinical inflammatory status in Rett syndrome.Semantic proximity Read ↗

Rett syndrome: a neurological disorder with metabolic components.Semantic proximity Read ↗

MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge: implications for Rett SyndromeSemantic proximity Read ↗

Novel plasmalogen derivative KIT-13 restores neurological function in a mouse model of Rett syndrome by reducing neuroinflammation and restoring mitochondrial functionSemantic proximity Read ↗

MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge.Semantic proximity Read ↗

Rett syndrome and MeCP2.Semantic proximity Read ↗

A proteomics approach to further highlight the altered inflammatory condition in Rett syndromeSemantic proximity Read ↗

Proteomic profiling reveals mitochondrial alterations in Rett syndrome.Semantic proximity Read ↗

MECP2 Dysfunction in Rett Syndrome: Molecular Mechanisms, Multisystem Pathology, and Emerging Therapeutic Strategies.Semantic proximity Read ↗

Rett syndrome: revised diagnostic criteria and nomenclature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.