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Article

Influenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice.

JCI insight - 26 Jan 2017

Cronk James C, Herz Jasmin, Kim Taeg S, Louveau Antoine, Moser Emily K, Sharma Ashish K, Smirnov Igor, Tung Kenneth S, Braciale Thomas J, Kipnis Jonathan

Abstract excerpt

Loss of function or overexpression of methyl-CpG-binding protein 2 (MeCP2) results in the severe neurodevelopmental disorders Rett syndrome and MeCP2 duplication syndrome, respectively. MeCP2 plays a critical role in neuronal function and the function of cells throughout the body. It has been previously demonstrated that MeCP2 regulates T cell function and macrophage response to multiple stimuli, and that...

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Identifiers

PMID: 28138553
DOI: 10.1172/jci.insight.88257
PMCID: PMC5256138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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