Article
Methyl-CpG-binding protein 2 mediates overlapping mechanisms across brain disorders.
Scientific reports - 17 Dec 2020
Bach Snow, Ryan Niamh M, Guasoni Paolo, Corvin Aiden P, El-Nemr Rania A, Khan Danyal, Sanfeliu Albert, Tropea Daniela
Abstract excerpt
MECP2 and its product, Methyl-CpG binding protein 2 (MeCP2), are mostly known for their association to Rett Syndrome (RTT), a rare neurodevelopmental disorder. Additional evidence suggests that MECP2 may underlie other neuropsychiatric and neurological conditions, and perhaps modulate common presentations and pathophysiology across disorders. To clarify the mechanisms of these interactions, we develop a method...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.