Article

Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3

2024-06-27

Abstract excerpt

<title>Abstract</title> <p>Thiamine and pyridoxine are essential B vitamins that serve as enzymatic cofactors in energy metabolism, protein and nucleic acid biosynthesis, and neurotransmitter production. In humans, thiamine transporters SLC19A2 and SLC19A3 primarily regulate cellular uptake of both vitamins. Genetic mutations in these transporters, which cause thiamine and pyridoxine deficiency, have been implica...

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Literature Corpus work: 58c90208-8e11-50bf-93d7-b15a91115c36
DOI: 10.21203/rs.3.rs-4363986/v1

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