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Article

Rare Diseases Linked to Mutations in Vitamin Transporters Expressed in the Human Blood-Brain Barrier.

Clinical pharmacology and therapeutics - 1 Dec 2024

Yee Sook Wah, Wang Joanne, Giacomini Kathleen M

Abstract excerpt

Recent advances have significantly enhanced our understanding of the role of membrane transporters in drug disposition, particularly focusing on their influence on pharmacokinetics, and consequently, pharmacodynamics. The relevance of these transporters in clinical pharmacology is well acknowledged. Recent research has also underscored the critical role of membrane transporters as targets in human diseases,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39234898
DOI: 10.1002/cpt.3433
PMCID: PMC11567784

Genes

SLC19A3
SLC52A2
SLC52A3
SLC5A6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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