Article

TER94 , the Drosophila Homologue of the ALS-related VCP gene, Influences Lifespan and Leads to a Decline in Motor Function

2020-08-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Valosin-Containing Protein (VCP) is an essential AAA+ ATPase with diverse functions within the cell. Mutations in the <italic>VCP</italic> gene have been detected in patients with familial amyotrophic lateral sclerosis (ALS). The aim of this study is to create a novel model of human neurodegenerative disease in <italic>Drosophila melanogaster</italic> by alterin...

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Literature Corpus work: 58c648ee-543c-5a1a-b450-7a8fc8cad577
DOI: 10.21203/rs.3.rs-60498/v1

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