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Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function 

2021-01-19

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<title>Abstract</title> <bold>Objective: </bold>Sequestosome 1 (p62/SQSTM1) is a multifunctional scaffold/adaptor protein encoded by the <italic>p62/SQSTM1</italic> gene with function in cellular homeostasis. Mutations in the <italic>p62/SQSTM1</italic> gene have been known to be associated with patients with Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), and Parkinson Disease (PD). The ai...

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Literature Corpus work: e1465b8a-582f-51fc-97f5-0466d0402560
DOI: 10.21203/rs.3.rs-62994/v4

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Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function DOI 10.21203/rs.3.rs-62994/v4Read

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Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function&nbsp;

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Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function