Article

Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry

2022-09-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Although men of African ancestry (AA) have the highest mortality rate from prostate cancer (PCa), relatively little is known about the germline variants that are associated with PCa risk in AA men. The goal of this study is to systematically evaluate rare, recurrent nonsynonymous variants across the exome for their association with PCa in AA men. <bold>Methods</...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 58b6b88e-31fc-5ab1-b7a4-fe84c9edc7dd
DOI: 10.21203/rs.3.rs-1832176/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestryDOI 10.21203/rs.3.rs-1832176/v2Read

Prostate cancer genetic risk and associated aggressive disease in men of African ancestrySemantic proximity Read

Prostate cancer genetic risk and associated aggressive disease in men of African ancestry.Semantic proximity Read

Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk.Semantic proximity Read

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.Semantic proximity Read

Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African menSemantic proximity Read

Review of prostate cancer genomic studies in AfricaSemantic proximity Read

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry.Semantic proximity Read

Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype StudySemantic proximity Read

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.Semantic proximity Read

A common variant associated with prostate cancer in European and African populationsSemantic proximity Read

Gene-Specific Cancer Patterns Among Pathogenic Germline Variant CarriersSemantic proximity Read

Correlation between Genomic Variants and Worldwide Epidemiology of Prostate Cancer.Semantic proximity Read