Article

Prostate cancer genetic risk and associated aggressive disease in men of African ancestry

2023-06-09

Abstract excerpt

<title>Abstract</title> <p>African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common risk variants contributing to a multiethnic polygenic risk score, with rare variants focused on a panel of roughly 20 pathogenic genes. Based on this knowledge, we were unable to determi...

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Literature Corpus work: c76a0282-6db4-5a0d-a0e8-20bab9a31b4e
DOI: 10.21203/rs.3.rs-2993516/v1

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