Article

Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men

2024-06-13

Abstract excerpt

<title>Abstract</title> <p>Prostate cancer (PCa) is highly heritable, with men of African ancestry at greatest risk and associated lethality. Lack of representation in genomic data means germline testing guidelines exclude for African men. Established that structural variations (SVs) are major contributors to human disease and prostate tumourigenesis, their role is under-appreciated in familial and therapeutic te...

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Literature Corpus work: 27cd6732-8255-5a18-bd0e-7d0456d05e39
DOI: 10.21203/rs.3.rs-4531885/v1

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