Article

Transcriptional Heterogeneity of Tumor-Associated High Endothelial Venules Defines Inflammatory and Stress-Metabolic States with Distinct Prognostic Associations

2026-02-20

Abstract excerpt

<title>Abstract</title> <p>Tumor-associated high endothelial venules (TA-HEVs) mediate lymphocyte trafficking into tumors and modulate the tumor microenvironment, with reported effects on clinical outcomes. However, reports have described discordant associations across cancers and microenvironmental contexts. Studies on state-specific, pan-cancer analyses of TA-HEV function remain limited. We integrated publicly...

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Literature Corpus work: 5899a0be-901c-54ae-a9d4-99f9f62dc083
DOI: 10.21203/rs.3.rs-8783132/v1

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