Article

Transcriptomic Profiles from Normal and Tumor Tissue Samples Reveal Distinct Venule Populations and Novel Tumor Endothelial Cell Markers in Breast Cancer

2025-06-27

Abstract excerpt

<h4>Background</h4> The breast tumor microenvironment (TME) is a complex milieu composed of many factors contributing to breast cancer (BC) heterogeneity and therapeutic resistance. Aberrant tumor vasculature in the TME limits nutrient and drug delivery, inhibits anti-tumor immunity, and contributes to a lack of cancer therapy efficacy. Utilizing publicly available scRNA-seq datasets, this study characterizes dif...

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Literature Corpus work: 4bdb103f-bdc2-5f87-b71c-0d1985a0a78f
DOI: 10.1101/2025.06.23.661087

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