Article

Tumor emboli-associated adaptive stress response signatures identify aggressive disease features in inflammatory breast cancer

2026-07-08

Abstract excerpt

Inflammatory breast cancer (IBC) is an aggressive breast cancer subtype characterized by tumor emboli, lymphovascular invasion (LVI), and early dissemination. Herein, we establish adaptive stress response (ASR) as a biologic feature linking stress adaptation to tumor emboli survival, lymphatic dissemination, therapeutic response, and disparities. Using a previously defined 226 ASR-related genes, complementary prec...

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Literature Corpus work: 9799d744-899a-5408-9660-01baf7a7ef5b
DOI: 10.64898/2026.07.06.734332

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