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Genome-wide association study of ischemic stroke risk in Sickle Cell confirms <i>ADAMTS2, CDK18</i>, uncovers 12 novel loci

2022-08-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Ischemic stroke is a common complication of sickle cell disease (SCD) and without screening or intervention can affect 11% of children with SCD before the age of 20. This study sought to find genetic biomarkers for risk of stroke occurring at younger ages. <h4>Methods</h4> Within the Trans-Omics for Precision Medicine (TOPMed), a genome-wide association study (GWAS) of ischemi...

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Literature Corpus work
58992a68-846c-54d8-93ec-5462d16259d4
DOI
10.1101/2022.08.22.22279082
Open publication

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Genome-wide association study of ischemic stroke risk in Sickle Cell confirms <i>ADAMTS2, CDK18</i>, uncovers 12 novel lociDOI 10.1101/2022.08.22.22279082
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