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Article

A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke.

Blood - 20 Dec 2012

Arning Astrid, Hiersche Milan, Witten Anika, Kurlemann Gerhard, Kurnik Karin, Manner Daniela, Stoll Monika, Nowak-Göttl Ulrike

Abstract excerpt

Pediatric stroke is a rare but highly penetrant disease with a strong genetic background. Although there are an increasing number of genome-wide association studies (GWASs) for stroke in adults, such studies for stroke of pediatric onset are lacking. Here we report the results of the first GWAS on pediatric stroke using a large cohort of 270 family-based trios. GWAS was performed using the Illumina 370 CNV single...

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Source

Identifiers

PMID: 22990015
DOI: 10.1182/blood-2012-07-442038

Genes

ADAMTS12
ADAMTS13
ADAMTS17
ADAMTS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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