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Article

Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposure

2024-07-10

Abstract excerpt

<h4>ABSTRACT</h4> Analyses of postmortem human brains and preclinical studies of rodents have identified somatostatin (SST)-positive interneurons as key elements that regulate the vulnerability to stress-related psychiatric disorders. Conversely, genetically induced disinhibition of SST neurons or brain region-specific chemogenetic activation of SST neurons in mice results in stress resilience. Here, we used RNA...

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Literature Corpus work
5880ce09-da6d-5c39-8ec7-3081fc236bfd
DOI
10.1101/2024.07.10.602959
Open publication

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Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposureDOI 10.1101/2024.07.10.602959
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