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Article

Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposure

2024-10-03

Abstract excerpt

<title>Abstract</title> <p>Analyses of postmortem human brains and preclinical studies of rodents have identified somatostatin (SST)-positive interneurons as key elements that regulate the vulnerability to stress-related psychiatric disorders. Conversely, genetically induced disinhibition of SST neurons or brain region-specific chemogenetic activation of SST neurons in mice results in stress resilience. Here, we...

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Literature Corpus work
5f387d31-d23d-5de4-98c4-d7923ecbf335
DOI
10.21203/rs.3.rs-4720297/v1
Open publication

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Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposureDOI 10.21203/rs.3.rs-4720297/v1
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