Article
Transcriptional profiles underlying vulnerability and resilience in rats exposed to an acute unavoidable stress.
Journal of neuroscience research - 1 Nov 2012
Benatti Cristina, Valensisi Cristina, Blom Joan M C, Alboni Silvia, Montanari Claudia, Ferrari Francesco, Tagliafico Enrico, Mendlewicz Julien, Brunello Nicoletta, Tascedda Fabio
Abstract excerpt
A complex interplay between gene and environment influences the vulnerability or the resilience to stressful events. In the acute escape deficit (AED) paradigm, rats exposed to an acute unavoidable stress (AUS) develop impaired reactivity to noxious stimuli. Here we assessed the behavioral and molecular changes in rats exposed to AUS. A genome-wide microarray experiment generated a comprehensive picture of...
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