Article

Allele-specific alternative splicing in human tissues

2020-05-05

Abstract excerpt

Alternative splicing is an RNA processing mechanism that affects most genes in human, contributing to disease mechanisms and phenotypic diversity. The regulation of splicing involves an intricate network of cis -regulatory elements and trans -acting factors. Due to their high sequence specificity, cis -regulation of splicing can be altered by genetic variants, significantly affecting splicing outcomes. Recently...

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Literature Corpus work: d6fa10ab-5985-5c34-b58b-0878c1fd2d21
DOI: 10.1101/2020.05.04.077255

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