Article
Cell Tree Rings: the structure of somatic evolution as a human aging timer
2022-12-16
Abstract excerpt
Biological age is typically estimated using biomarkers whose states have been observed to correlate with chronological age. A persistent limitation of such aging clocks is that it is difficult to establish how the biomarker states are related to the mechanisms of aging. Somatic mutations could potentially form the basis for a more fundamental aging clock since the mutations are both markers and drivers of aging an...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 586b2063-bc29-5c86-80bd-ebb333846337
- DOI
- 10.1101/2022.12.14.520419