Back to search

Article

Modeling alternative translation initiation sites in plants reveals evolutionarily conserved <i>cis</i> -regulatory codes in eukaryotes

2023-10-21

Abstract excerpt

mRNA translation relies on identifying translation initiation sites (TISs) in mRNAs. Alternative TISs are prevalent across plant transcriptomes, but the mechanisms for their recognition are unclear. Using ribosome profiling and machine learning, we developed models for predicting alternative TISs in Arabidopsis thaliana and tomato ( Solanum lycopersicum ). Distinct feature sets were predictive of AUG and non-AUG...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
584aa332-160f-5da6-aa4f-4ab8a100faf2
DOI
10.1101/2023.10.20.563379
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Modeling alternative translation initiation sites in plants reveals evolutionarily conserved <i>cis</i> -regulatory codes in eukaryotesDOI 10.1101/2023.10.20.563379
Mammalian Alternative Translation Initiation Is Mostly Nonadaptive.Semantic proximity
Quantitative analysis of mammalian translation initiation sites by FACS-seq.Semantic proximity
Tandem repeats ubiquitously flank and select translation initiation sitesSemantic proximity
Functional characterization of 5’ UTR <i>cis</i> -acting sequence elements that modulate translational efficiency in <i>P. falciparum</i> and humansSemantic proximity
Direct analysis of ribosome targeting illuminates thousand-fold regulation of translation initiationSemantic proximity
Decoding the Sequence Requirements for Translation InitiationSemantic proximity
­ Functional Characterization of 5’ UTR Cis-Acting Sequence Elements That Modulate Translational Efficiency in P. Falciparum and HumansSemantic proximity
NeuroTIS+: An Improved Method for Translation Initiation Site Prediction in Full-Length mRNA Sequence via Structural InformationSemantic proximity
Comprehensive profiling of translation initiation in influenza virus infected cellsSemantic proximity
<i>uORF-Tools</i> – Workflow for the determination of translation-regulatory upstream open reading framesSemantic proximity
Mechanisms Leading to the Loss of AUG Codon Function as a Translation InitiatorSemantic proximity
N-terminal Proteomics and Ribosome Profiling Provide a Comprehensive View of the Alternative Translation Initiation Landscape in Mice and MenSemantic proximity
Select a neighboring publication to make it the new centre.