Astroglial FMRP modulates synaptic signaling and behavior phenotypes in FXS mouse model.

Abstract excerpt

Fragile X syndrome (FXS) is one of the most common inherited intellectual disability (ID) disorders, in which the loss of FMRP protein induces a range of cellular signaling changes primarily through excess protein synthesis. Although neuron-centered molecular and cellular events underlying FXS have been characterized, how different CNS cell types are involved in typical FXS synaptic signaling changes and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Astrocytes
• Share to Disease Models, Animal