Article

Understanding the Role of Elastic Modulus in the Relationship Between Second Harmonic Generation Scattering and Tumor Cell Motility

2020-09-09

Abstract excerpt

<title>Abstract</title> <p>Background Second harmonic generation (SHG) is an intrinsic optical property of fibrillar collagen. SHG directionality is quantified by F/B, the ratio of forward- to backward-propagating signal, which is affected by collagen fiber internal structure, specifically the diameter, spacing, and disorder of fibrils within a collagen fiber. We have previously shown that F/B of primary invasiv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5809bd51-7c4e-5bfa-88be-9a0f883821f6
DOI: 10.21203/rs.2.23511/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Understanding the Role of Elastic Modulus in the Relationship Between Second Harmonic Generation Scattering and Tumor Cell MotilityDOI 10.21203/rs.2.23511/v2Read

Tumor extracellular matrix: lessons from the second-harmonic generation microscopySemantic proximity Read

Dynein-Powered Cell Locomotion Guides Metastasis of Breast CancerSemantic proximity Read

Mechanotransduction-Induced Gene Expression Reveals Activation of TGFβ/SKIL/TAZ Axis and Supports Invasive Phenotype in Triple-Negative Breast Cancer.Semantic proximity Read

Physical network regimes of 3D fibrillar collagen networks trigger invasive phenotypes of breast cancer cells.Semantic proximity Read

The size-speed-force relationship governs migratory cell response to tumorigenic factorsSemantic proximity Read

Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal ModelSemantic proximity Read

Patient-derived glioblastoma cells (GBM) exhibit distinct biomechanical profiles associated with altered activity in the cytoskeleton regulatory pathwaySemantic proximity Read

Cancer Cell Motility Through Unjamming Impacts Metastatic RiskSemantic proximity Read

Matrix Stiffness Modulates Metabolic Interaction Between Human Stromal and Breast Cancer Cells to Stimulate Epithelial MotilitySemantic proximity Read

Cancer Cell Migration: Integrated Roles of Matrix Mechanics and Transforming PotentialSemantic proximity Read

Mechanical Fingerprints in Breast Cancer Research: A Multimodal Experimental ApproachSemantic proximity Read

Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinomaSemantic proximity Read