Article

Tumor extracellular matrix: lessons from the second-harmonic generation microscopy

2021-03-22

Abstract excerpt

Abstract Extracellular matrix (ECM) represents more than a mere intercellular cement. It is physiologically active in cell communication, adhesion and proliferation. Collagen is the most abundant protein, making up to 90% of ECM, and 30% of total protein weight in humans. Second-harmonic generation (SHG) microscopy represents an important tool to study collagen organization of ECM in freshly unfixed tissues and pa...

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Literature Corpus work: 2d4825d5-faa2-5b56-adf0-5fbb35962c9d
DOI: 10.1186/s42047-021-00089-0

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