Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Cell Migration: Integrated Roles of Matrix Mechanics and Transforming Potential

27 May 2011

Abstract excerpt

Significant progress has been achieved toward elucidating the molecular mechanisms that underlie breast cancer progression; yet, much less is known about the associated cellular biophysical traits. To this end, we use time-lapsed confocal microscopy to investigate the interplay among cell motility, three-dimensional (3D) matrix stiffness, matrix architecture, and transforming potential in a mammary epithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cellular Mechanics and Interactions
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21647371
DOI: 10.1371/journal.pone.0020355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Cell Migration: Integrated Roles of Matrix Mechanics and Transforming PotentialPMID 21647371Read ↗

Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancerSemantic proximity Read ↗

2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagenSemantic proximity Read ↗

Decoding Single Cell Morphology in Osteotropic Breast Cancer Cells for Dissecting Their Migratory, Molecular and Biophysical HeterogeneitySemantic proximity Read ↗

The size-speed-force relationship governs migratory cell response to tumorigenic factorsSemantic proximity Read ↗

Modeling and predictions of biphasic mechanosensitive cell migration altered by cell-intrinsic properties and matrix confinement.Semantic proximity Read ↗

Real-time motion analysis reveals cell directionality as an indicator of breast cancer progression.Semantic proximity Read ↗

Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell matrix interaction in 3DSemantic proximity Read ↗

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini ReviewSemantic proximity Read ↗

Filopodia-mediated basement membrane assembly at pre-invasive tumor boundariesSemantic proximity Read ↗

Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal ModelSemantic proximity Read ↗

Adhesion tunes speed and persistence by coordinating protrusions and extracellular matrix remodelingSemantic proximity Read ↗

Cancer Cell Motility Through Unjamming Impacts Metastatic RiskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.