Article

Computational Identification of Ligand-Receptor Pairs that Drive Human Astrocyte Development

2022-06-01

Abstract excerpt

<h4>SUMMARY</h4> Extrinsic signaling between diverse cell types is crucial to nervous system development. Ligand binding is a key driver of developmental processes, but it remains a significant challenge to disentangle how collections of these signals act cooperatively to affect changes in recipient cells. In the developing human brain, cortical progenitors transition from neurogenesis to gliogenesis in a stereot...

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Literature Corpus work: 57c969b0-e2d3-524b-9d26-e0e48a47e1db
DOI: 10.1101/2022.05.31.491513

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