Article

Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids

2025-12-14

Abstract excerpt

Tissues develop and function within a highly complex microenvironment, where diverse cell types interact in tightly regulated spatial and temporal patterns 1,2 . Through distinct, relay-like waves of activity, these cells collectively shape tissue formation, ensuring that each component emerges in the right place at the right time 1,2 . Such coordinated cues establish the structural and biochemical framework tha...

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Literature Corpus work: fcb3f4bb-3a4c-5aed-9b3c-db862fd9d063
DOI: 10.64898/2025.12.13.694117

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