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A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

2021-05-26

Abstract excerpt

<title>Abstract</title> <p>Human organogenesis remains relatively unexplored for ethical and practical reasons. Here we report the establishment of a single cell transcriptome atlas of the human fetal pancreas between 7 and 10 post-conceptional weeks of development. To interrogate cell-cell interactions we developed InterCom, an R-Package for identifying receptors-ligand pairs and their downstream effects. We fur...

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Literature Corpus work: 7e5ea4ba-669d-5ce2-9005-d82faa086239
DOI: 10.21203/rs.3.pex-1430/v2

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