Article

Sex Differences in Blood Pressure and the Kidney Cortex Transcriptome in Nonhuman Primates

2021-10-28

Abstract excerpt

<title>Abstract</title> <p>Hypertension is a complex disease influenced by sex, and genetic and environmental factors. Blood pressure (BP) is a continuous trait that is heritable in primates, including humans and baboons. The kidneys play a role in systemically regulating BP. Sex differences in BP onset and control with antihypertensive drug therapies have been observed in humans and rodents. Hypertension studies...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 57a114c1-bf27-5210-b533-eff46ac51134
DOI: 10.21203/rs.3.rs-723028/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex Differences in Blood Pressure and the Kidney Cortex Transcriptome in Nonhuman PrimatesDOI 10.21203/rs.3.rs-723028/v3Read

Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.Semantic proximity Read

Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications.Semantic proximity Read

Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs.Semantic proximity Read

Intersecting Transcriptomic Landscapes of Hypertension and Kidney Function in African American WomenSemantic proximity Read

Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidneySemantic proximity Read

The impact of testosterone on paraventricular nucleus gene expression in male and female spontaneously hypertensive ratsSemantic proximity Read

Single-Cell RNA Sequencing Reveals Heterogeneity Among Adult Mouse, Primate and Human Kidney CellsSemantic proximity Read

Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespanSemantic proximity Read

Dissecting the comprehensive relationship between blood pressure and bone mass: the observational association and pleiotropic drug targetsSemantic proximity Read

Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure.Semantic proximity Read

Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAsSemantic proximity Read

Sexual Dimorphism in Gene Expression: A Genome-Wide Study of Tissue and Chromosome DependenciesSemantic proximity Read