Article
Genetic risk effects on psychiatric disorders act in sets
2025-07-23
Abstract excerpt
Genetic studies of psychiatric disorders have typically assumed that all genetic effects contribute additively to disease liability. However, it is likely that psychiatric disorders have unrecognized subtypes, where synergistic sets of risk variants co-occur within certain cases more than expected under additivity. The existence of synergistic sets induces a structured form of statistical interactions called coord...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 5797f2f1-4c10-5608-9f78-01decd0d1f57
- DOI
- 10.1101/2025.07.23.25332043