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Article

Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders.

Biological psychiatry - 1 Jan 2021

Lee Phil H, Feng Yen-Chen A, Smoller Jordan W

Abstract excerpt

Genome-wide analyses of common and rare genetic variations have documented the heritability of major psychiatric disorders, established their highly polygenic genetic architecture, and identified hundreds of contributing variants. In recent years, these studies have illuminated another key feature of the genetic basis of psychiatric disorders: the important role and pervasive nature of pleiotropy. It is now clear...

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Identifiers

PMID: 33131714
DOI: 10.1016/j.biopsych.2020.09.026
PMCID: PMC7898275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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