Article
Uncovering the genetic underpinnings for different psychiatric disorder combinations.
Psychological medicine - 12 Sept 2025
Yin Liangying, Liu Menghui, Shi Yujia, Zhang Ruoyu, Lui Simom, So Hon-Cheong
Abstract excerpt
BACKGROUND: Psychiatric disorders are highly heterogeneous. It is clinically valuable to distinguish psychiatric disorders by the presence or absence of a specific comorbid condition. METHODS: We employed a novel algorithm (CombGWAS) to decipher the genetic basis of psychiatric disorder combinations using genome-wide association studies summary statistics. We focused on comorbidities and combinations of diseases,...
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