Article

Genetically encoded fluorescent reporter for polyamines

2024-08-26

Abstract excerpt

Polyamines are abundant and evolutionarily conserved metabolites that are essential for life. Dietary polyamine supplementation extends life-span and health-span. Dysregulation of polyamine homeostasis is linked to Parkinson’s disease and cancer, driving interest in therapeutically targeting this pathway. However, measuring cellular polyamine levels, which vary across cell types and states, remains challenging. We...

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Identifiers and source

Literature Corpus work: 5763fc4d-dbc7-5d3e-8e8f-08fdaa92e76c
DOI: 10.1101/2024.08.24.609500

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