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Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

5 Jul 2015

Abstract excerpt

The polyamines (PAs) spermidine, spermine, putrescine and cadaverine are an essential class of metabolites found throughout all kingdoms of life. In this comprehensive review, we discuss their metabolism, their various intracellular functions and their unusual and conserved regulatory features. These include the regulation of translation via upstream open reading frames, the over-reading of stop codons via...

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PMID: 26156863
DOI: 10.1016/j.jmb.2015.06.020

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